Botox shots aim to ease chronic jaw pain in new study
NCT ID NCT07668375
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether injecting botulinum toxin (Botox) into jaw muscles can reduce pain and improve mouth opening in people with temporomandibular joint (TMJ) myofascial pain. 118 adults with at least moderate pain for over a month received injections in their masseter and temporalis muscles. The goal was to measure pain relief and how wide they could open their mouths after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Botulinum Toxin-A (Botox-like injection)
What this could lead to
If it works, this could offer a non-surgical option to ease jaw pain and improve mouth opening for people with TMJ disorders.
What could go wrong
This is a small, single-site completed trial. Results may not apply to everyone, and risks include injection site reactions or muscle weakness.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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PAEC General Hospital, Islamabad
Islamabad, Islamabad, 44000, Pakistan