Botox eases jaw pain in small trial

NCT ID NCT06840730

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether Botox injections can reduce pain and improve jaw movement in people with chronic jaw muscle pain that didn't get better with standard treatments. Twenty-five participants received Botox injections into their jaw muscles. Researchers measured pain levels, mouth opening, and inflammatory markers in blood and saliva before and 28 days after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Botulinum toxin A (Botox)
What this could lead to
If successful, this could point toward a non-surgical treatment option for people with chronic jaw muscle pain that hasn't improved with standard care.
What could go wrong
This is a small, early exploratory study with only 25 participants and no control group. Results may not apply to everyone, and Botox injections carry risks like temporary muscle weakness or bruising.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hacettepe University

    Ankara, Turkey (Türkiye)

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