Botox before hernia surgery: a simpler, safer repair?

NCT ID NCT07349628

Completed Symptom relief Sponsor: Azienda Sanitaria Locale Napoli 2 Nord Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether injecting botulinum toxin A (like Botox) into the abdominal muscles before surgery can make it easier to close complex incisional hernias. The idea is that relaxing the muscles allows doctors to repair the hernia without needing more extensive procedures. The study followed 32 adults undergoing planned hernia repair and measured how often the hernia could be closed with a simpler technique, as well as complication rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: botulinum toxin A
What this could lead to: If successful, this approach could make complex hernia repairs safer and less invasive, reducing the need for more extensive surgery.
What could go wrong: This is a small, observational study with only 32 participants, so results may not apply to everyone. Botulinum toxin A can cause temporary muscle weakness or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Incisional Hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INCISIONAL HERNIA

Contacts and locations

Locations

Aslnapoli2Nord

Naples, Naples, 80131, Italy

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