Botox vs. scalpel: which heals anal fissures better?

NCT ID NCT07568314

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study compares two treatments for chronic anal fissure, a painful condition. One group gets Botox injections to relax the muscle; the other has a minor surgery called lateral internal sphincterotomy. Researchers will track healing, pain, and side effects in 90 adults over 3 months to see which option works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Botulinum toxin type A (Botox) injection
What this could lead to
If this trial shows Botox works as well as surgery, patients may have a less invasive option for chronic anal fissure relief.
What could go wrong
This is a small, single-center study. Botox effects are temporary, and surgery carries risks like incontinence. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Islamabad Medical and Dental College

    Islamabad, Federal, 44000, Pakistan

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