Botox vs. scalpel: which heals anal fissures better?

NCT ID NCT07568314

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for chronic anal fissure, a painful condition. One group gets Botox injections to relax the muscle; the other has a minor surgery called lateral internal sphincterotomy. Researchers will track healing, pain, and side effects in 90 adults over 3 months to see which option works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum toxin type A (Botox) injection

What this could lead to

If this trial shows Botox works as well as surgery, patients may have a less invasive option for chronic anal fissure relief.

What could go wrong

This is a small, single-center study. Botox effects are temporary, and surgery carries risks like incontinence. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Islamabad Medical and Dental College

    RECRUITING

    Islamabad, Federal, 44000, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••