Botox or botox plus surgery: which heals anal fissures better?
NCT ID NCT07665528
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two treatments for chronic anal fissure, a painful tear in the anal canal. One group gets Botox injections alone to relax the muscle, while the other gets Botox plus a minor surgery to remove scar tissue and repair the area. Researchers will track healing, pain, and recurrence in 108 adults over several weeks to see which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Botulinum toxin type A (Botox) injection, with or without fissurectomy and anoplasty surgery
What this could lead to
If the combined approach works better, it could offer a more effective, sphincter-preserving treatment for chronic anal fissure with lower recurrence.
What could go wrong
This is a small, early-stage trial with only 108 participants, so results may not apply to everyone. The added surgery also carries risks like infection or incontinence.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Islamabad Medical and Dental College
RECRUITINGIslamabad, Federal, 44000, Pakistan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••