Botox shot may ease thumb arthritis pain for months
NCT ID NCT03187626
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a single ultrasound-guided injection of Botox into the thumb joint, combined with a splint, can reduce pain in people with base-of-thumb osteoarthritis. Sixty adults with moderate to severe pain received either Botox or a saline placebo injection. The main goal was to see if pain improved three months later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- botulinum toxin A (Botox)
- What this could lead to
- If it works, this could offer a new, non-surgical option to ease thumb arthritis pain for several months.
- What could go wrong
- This is a small pilot study, so results may not apply to everyone. Pain relief may be short-lived or no better than a placebo injection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Assistance Publique - Hôpitaux de Paris, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, Hôpital Cochin
Paris, Paris, 75014, France
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