Botox beyond the face: could jaw injections ease synkinesis?
NCT ID NCT07295288
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding Botox injections to the jaw (masseter) and temple (temporalis) muscles can improve symptoms of facial synkinesis—a condition where facial muscles move involuntarily after nerve injury. Fifty adults will receive standard Botox treatment alone or with extra injections into these non-facial muscles, using a crossover design so each person acts as their own control. The goal is to see if this approach reduces unwanted movements, headaches, and jaw tightness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum Toxin Type A (Botox)
- What this could lead to
- If it works, this could offer a simple addition to standard Botox treatment to better manage unwanted facial movements and related jaw pain or headaches.
- What could go wrong
- This is a small, early-phase study (50 people) testing an off-label use. The added benefit may be small or not apply to everyone, and there is a risk of temporary muscle weakness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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