Herbal sleep aid challenges melatonin in new study

NCT ID NCT06894108

Completed Symptom relief Sponsor: Nutraceuticals Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a proprietary blend of botanical extracts against melatonin in 89 healthy women aged 35-55 who reported poor sleep. Participants took either the botanical supplement or 1mg of melatonin each night before bed. The goal was to see if the botanical extract could improve sleep quality more than melatonin, using a sleep scale and wearable device data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: botanical extract blend
What this could lead to: If it works, this could offer a natural alternative to melatonin for better sleep.
What could go wrong: This is a small, completed trial with only 89 participants, so results may not apply to everyone. Dietary supplements are not as strictly regulated as drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SLEEP

Contacts and locations

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Locations

Nutraceuticals Research Institute

Huntsville, Alabama, 35801, United States

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