First human test of new cancer drug shows promise and risks

NCT ID NCT03396445

Summary

This early-stage study aimed to find a safe dose and understand how the body processes a new experimental drug called boserolimab. It involved 182 adults with advanced cancers, including lung and breast cancer, who had run out of standard treatment options. Researchers tested boserolimab given alone and in combination with other cancer drugs to check for side effects and see how the drug behaves in the body.

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Contacts and locations

Locations

  • Antoni van Leeuwenhoek Ziekenhuis ( Site 0003)

    Amsterdam, North Holland, 1066 CX, Netherlands

  • Bradfordhill-Clinical Area ( Site 0501)

    Santiago, Region M. de Santiago, 8420383, Chile

  • Centro Integral Oncologico Clara Campal START Madrid ( Site 0040)

    Madrid, 28050, Spain

  • Erasmus MC ( Site 0031)

    Rotterdam, South Holland, 3015 GD, Netherlands

  • FALP-UIDO ( Site 0502)

    Santiago, Region M. de Santiago, 6900941, Chile

  • Florida Cancer Specialists ( Site 0002)

    Sarasota, Florida, 34232, United States

  • Hadassah Ein Kerem Medical Center ( Site 0010)

    Jerusalem, 9112001, Israel

  • Hospital Universitario Fundacion Jimenez Diaz ( Site 0041)

    Madrid, 28040, Spain

  • Hospital Universitario Quiron Madrid ( Site 0043)

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Instituto Catalan de Oncologia - ICO ( Site 0044)

    Barcelona, 08916, Spain

  • Koo Foundation Sun Yat-Sen Cancer Center ( Site 0802)

    Taipei, 112, Taiwan

  • National Taiwan University Hospital-Oncology ( Site 0801)

    Taipei, 100, Taiwan

  • Seoul National University Hospital-Internal Medicine ( Site 0702)

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System-Medical oncology ( Site 0701)

    Seoul, 03722, South Korea

  • Soroka Medical Center-Oncology ( Site 0012)

    Beersheba, 8400000, Israel

  • The Chaim Sheba Medical Center - Oncology Institute ( Site 0001)

    Ramat Gan, 5265601, Israel

  • The West Clinic, P.C. ( Site 0021)

    Germantown, Tennessee, 38138, United States

  • University of South Alabama, Mitchell Cancer Institute ( Site 0020)

    Mobile, Alabama, 36604, United States

Conditions

Explore the condition pages connected to this study.