New hope for bone loss after spinal injury: drug combo may protect knees

NCT ID NCT05101018

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study compares two osteoporosis medications—romosozumab followed by denosumab versus denosumab alone—in 40 adults with a spinal cord injury that happened less than six months ago. The goal is to see which approach better maintains bone density around the knee over two years. Participants must be 18–55 years old and have no history of heart disease, stroke, or bone cancer.

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Contacts and locations

Locations

  • James J. Peters VA Medical Center

    The Bronx, New York, 10468, United States

  • Kessler Institute for Rehabilitation

    West Orange, New Jersey, 07052, United States

Conditions

Explore the condition pages connected to this study.