New bone graft shows promise for mending tough leg breaks
NCT ID NCT04960722
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a new bone graft material (OIF/β-TCP) in 35 people with severe open fractures of the shin bone (tibia). The goal was to see if it helps bones heal when they are slow to mend. Participants were followed for up to 52 weeks after the graft was implanted.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- OIF/β-TCP (BiG001) bone graft
- What this could lead to
- If successful, this could offer a new option to help heal severe leg fractures that are slow to mend.
- What could go wrong
- This is a small, early study with only 35 participants. The results may not apply to everyone, and there is always a risk the graft may not work or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
BioGend Therapeutics
Taipei, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.