New combo therapy targets tough lung cancer cases

NCT ID NCT07111520

Recruiting now Disease control Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 32 times

Summary

This study tests two experimental drugs, BNT326 and BNT327, together in adults with advanced non-small cell lung cancer that has spread or come back. The goal is to find the best dose and see if the combination can shrink tumors and control the disease. About 420 participants will take part across multiple sites.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Adana City Hospital
RECRUITING

Adana, 01230, Turkey (Türkiye)
Affiliated Hospital of Hebei University
RECRUITING

Baoding, 071000, China
Anhui Chest Hospital
RECRUITING

Hefei, 230022, China
Anhui Provincial Cancer Hospital
RECRUITING

Hefei, 230088, China
Ankara Memorial Hospital
RECRUITING

Ankara, 06520, Turkey (Türkiye)
Azienda Ospedaliera Universitaria Careggi
RECRUITING

Florence, 50134, Italy
Azienda Ospedaliero - Universitaria Nazionale Santi Antonio e Biagio e Cesare Arrigo
RECRUITING

Alessandria, 15100, Italy
Baskent University Adana Application and Research Center
RECRUITING

Adana, 01240, Turkey (Türkiye)
Beijing GoBroad Hospital
RECRUITING

Beijing, 102200, China
Cancer Research SA
RECRUITING

Adelaide, 5000, Australia
Centrum Medyczne Pratia Poznan
RECRUITING

Poznan, 60-192, Poland
Chongqing University Cancer Hospital
RECRUITING

Chongqing, 400030, China
Cleveland Clinic Taussig Cancer Institute Case Comprehensive Cancer Center
RECRUITING

Cleveland, Ohio, 44195, United States
Clinica Universidad de Navarra
RECRUITING

Madrid, 31008, Spain
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Dr. Abdurrahman Yurtaslan Ankara Oncology Research and Training Hospital, Clinical Research Center
RECRUITING

Ankara, 06105, Turkey (Türkiye)
Gazi University Medical Faculty
RECRUITING

Ankara, 06500, Turkey (Türkiye)
Goztepe Prof. Dr. Suleyman Yalcin City Hospital
RECRUITING

Istanbul, 34722, Turkey (Türkiye)
Hacettepe University Medical Faculty
RECRUITING

Ankara, 06100, Turkey (Türkiye)
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Quironsalud Malaga
RECRUITING

Málaga, 29004, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario HM Madrid Sanchinarro
RECRUITING

Madrid, 28050, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
Hubei Cancer Hospital
RECRUITING

Wuhan, 430079, China
Institute of Oncology, ARENSIA Exploratory Medicine
RECRUITING

Chisinau, 2025, Moldova
Jinan Central Hospital
RECRUITING

Jinan, 250013, China
John Flynn Private Hospital
RECRUITING

Tugun, 4224, Australia
Koc University Hospital
RECRUITING

Istanbul, 34010, Turkey (Türkiye)
Med-Polonia Sp. z o.o.
RECRUITING

Poznan, 60-693, Poland
Medical Park Seyhan Hospital
RECRUITING

Adana, 01140, Turkey (Türkiye)
Memorial Antalya Hastanesi
RECRUITING

Antalya, 07020, Turkey (Türkiye)
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Mersin City Education and Research Hospital
RECRUITING

Mersin, 33330, Turkey (Türkiye)
Moffit Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
NEXT Virginia
RECRUITING

Fairfax, Virginia, 22031, United States
Northern Centre for Cancer Care
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
Northern Jiangsu People's Hospital
RECRUITING

Yangzhou, 225001, China
Pratia MCM Krakow
RECRUITING

Krakow, 30-727, Poland
Provita Prolife
RECRUITING

Tomaszów Mazowiecki, 97-200, Poland
Royal Free Hospital
RECRUITING

London, NW3 2QG, United Kingdom
Royal Marsden Hospital
RECRUITING

London, SW3 6JJ, United Kingdom
Royal Marsden Hospital-Sutton
RECRUITING

Sutton, SM2 5PT, United Kingdom
Sakarya Training and Research Hospital
RECRUITING

Sakarya, 54290, Turkey (Türkiye)
Shanghai East Hospital
RECRUITING

Shanghai, 200120, China
Shanghai GoBroad Cancer Hospital
RECRUITING

Shanghai, 200120, China
St George Private Hospital
RECRUITING

Kogarah, 2217, Australia
Stanford Cancer Institute
RECRUITING

Stanford, California, 94305, United States
The Affiliated Hospital of Qingdao University
RECRUITING

Qingdao, 266003, China
The First Affiliated Hospital School of Clinical Medicine of Guangdong Pharmaceutical University
RECRUITING

Guangzhou, 510080, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, 230022, China
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, 510163, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, 330006, China
The First Affiliated Hospital of Soochow University
RECRUITING

Suzhou, 215006, China
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING

Xinxiang, 453100, China
The First Hospital of Jilin University
RECRUITING

Changchun, 130021, China
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, 330006, China
The Second Hospital of Anhui Medical University
RECRUITING

Hefei, 230601, China
Tianjin Medical University Cancer Institute & Hospital
RECRUITING

Tianjin, 300060, China
University of Texas M. D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Universitätsklinikum Carl Gustav Carus TU Dresden
RECRUITING

Dresden, 01307, Germany
Universitätsklinikum Freiburg
RECRUITING

Freiburg im Breisgau, 79106, Germany
West China Hospital, Sichuan University
RECRUITING

Chengdu, 611135, China
Westmead Hospital
RECRUITING

Westmead, 2145, Australia
Xiangyang Central Hospital
RECRUITING

Xiangyang, 441138, China
Yale University
RECRUITING

New Haven, Connecticut, 06511, United States
Yeditepe University Medical School Hospital
RECRUITING

Istanbul, 31755, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER NON-SMALL CELL LUNG CANCER