Simple blood test could revolutionize traumatic brain injury diagnosis
NCT ID NCT07455136
First seen Jun 25, 2026 · Last updated Jul 29, 2026 · Updated 5 times
Summary
This study aims to create a blood test that helps doctors quickly diagnose traumatic brain injury (TBI) and predict how patients will recover. Researchers will collect blood samples from 2,000 adults with suspected TBI in emergency rooms and hospitals. The goal is to find specific markers in the blood that can confirm injury and monitor for complications, potentially reducing the need for CT scans and improving patient care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test that helps doctors quickly diagnose traumatic brain injury and predict recovery, reducing reliance on CT scans.
- What could go wrong
- This is an early-stage study focused on developing and validating the test, not yet proving it works in routine practice. The test may not be accurate enough to replace current methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Atrium Health - Carolina Medical Center
RECRUITINGCharlotte, North Carolina, 28203, United States
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Brown University
NOT_YET_RECRUITINGProvidence, Rhode Island, 29903, United States
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Goodman Campbell Brain and Spine/Ascension
NOT_YET_RECRUITINGCarmel, Indiana, 46032, United States
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Medical College of Wisconsin
NOT_YET_RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Northwell Health - Department Of Neurosurgery
NOT_YET_RECRUITINGManhasset, New York, 11030, United States
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University Of California Davis, Neurological Surgery
NOT_YET_RECRUITINGSacramento, California, 95817, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94110, United States
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University of Cincinnati
RECRUITINGCincinnati, Ohio, 45229, United States
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University of Pennsylvania Medical Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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University of Utah
NOT_YET_RECRUITINGSalt Lake City, Utah, 84132, United States
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University of Wisconsin
WITHDRAWNMadison, Wisconsin, 53792, United States
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Vanderbilt University Medical Center
NOT_YET_RECRUITINGNashville, Tennessee, 37203, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could music be medicine for the injured brain?
- Can blood markers predict brain injury outcomes?
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- Can brain training help TBI patients remember to remember?
- Can a natural protein fragment help the brain heal after severe injury?