Simple blood test could revolutionize traumatic brain injury diagnosis

NCT ID NCT07455136

First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study aims to create a blood test that helps doctors quickly diagnose traumatic brain injury (TBI) and predict how patients will recover. Researchers will collect blood samples from 2,000 adults with suspected TBI in emergency rooms and hospitals. The goal is to find specific markers in the blood that can confirm injury and monitor for complications, potentially reducing the need for CT scans and improving patient care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test that helps doctors quickly diagnose traumatic brain injury and predict recovery, reducing reliance on CT scans.

What could go wrong

This is an early-stage study focused on developing and validating the test, not yet proving it works in routine practice. The test may not be accurate enough to replace current methods.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health - Carolina Medical Center

    RECRUITING

    Charlotte, North Carolina, 28203, United States

  • Brown University

    NOT_YET_RECRUITING

    Providence, Rhode Island, 29903, United States

  • Goodman Campbell Brain and Spine/Ascension

    NOT_YET_RECRUITING

    Carmel, Indiana, 46032, United States

  • Medical College of Wisconsin

    NOT_YET_RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Northwell Health - Department Of Neurosurgery

    NOT_YET_RECRUITING

    Manhasset, New York, 11030, United States

  • University Of California Davis, Neurological Surgery

    NOT_YET_RECRUITING

    Sacramento, California, 95817, United States

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94110, United States

  • University of Cincinnati

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45229, United States

  • University of Pennsylvania Medical Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Utah

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84132, United States

  • University of Wisconsin

    WITHDRAWN

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University Medical Center

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States