Can blood filtration save kids with sepsis? new trial aims to find out

NCT ID NCT05595239

Not yet recruiting Disease control Sponsor: Children's Hospital of Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares three blood purification methods in 120 children with sepsis, aged 29 days to 18 years. The goal is to see which method best reduces inflammatory chemicals and organ damage. Researchers will also check survival rates at 28 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood purification (CVVH, TPE+CVVH, or HP+CVVH) using a device
What this could lead to: If successful, this could identify the best blood purification method to reduce harmful inflammation and improve survival in children with sepsis.
What could go wrong: This is an early-stage study with only 120 children, so results may not apply to all cases. The treatments are complex and carry risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD PURIFICATION SEPSIS

Contacts and locations

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Locations

Lu Guoping

Shanghai, Shanghai Municipality, 201102, China

Contact Phone: •••-•••-•••• Email: •••••@•••••

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