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Could a blood test reveal hidden colon growths before cancer strikes?

NCT ID NCT07881549

Diagnosis Sponsor: Region Skane Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 19, 2026 · Last updated Oct 20, 2026 · Updated 1 time

Summary

Colorectal cancer often develops slowly from precancerous polyps and can cause no symptoms. The ProScreen study asks whether proteins measured in a blood sample can help tell apart people with advanced precancerous growths, people with colorectal cancer, and people without these conditions. Researchers recruit 150 people scheduled for a colonoscopy, collect blood samples, and compare protein patterns across the three groups based on colonoscopy findings. The study tests no experimental treatment; its goal is to learn whether protein signatures could support better blood tests for prevention and early detection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If protein patterns prove reliable, this could support a simpler blood test for spotting advanced precancerous growths and early colorectal cancer, potentially before symptoms appear.
What could go wrong
This is an early, small study of 150 people. Protein patterns may not separate the groups clearly, may not hold up in larger or more diverse populations, and any blood test would still need years of validation before routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2026

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for a colonoscopy due to a positive FIT test taken in the national screening program or patients with confirmed colorectal adenomas or cancer will be invited to participate in the study

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Scheduled for a coloscopy Exclusion Criteria: * History of colorectal cancer, other cancer or inflammatory bowel disease

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Conditions

The condition(s) this trial relates to.

adenoma colorectal adenoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal adenoma Colorectal cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Skåne University Hopsital, Malmö

    Malmö, 20502, Sweden

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