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Could a tiny blood molecule reveal how addiction rewires the brain?

NCT ID NCT07830680

NEW Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers at Nantes University Hospital are studying whether adults with food addiction or sexual addiction have different levels of a blood molecule called miR-10a-5p compared with healthy adults of similar age and sex. The study enrolls 28 participants, including patients already in care and healthy controls. Everyone gives one blood sample, which researchers analyze to compare microRNA expression and look for links between these molecules and clinical symptoms. The goal is to understand the biology of behavioral addictions and whether microRNAs could serve as future biomarkers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers find a distinct microRNA pattern in people with food or sexual addiction, it could point toward a future blood test or a new target for treatment.
What could go wrong
This small pilot study only looks for a correlation in blood samples, so it cannot prove that microRNAs cause or drive these behaviors. Any pattern found may not hold up in larger groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with food or sexual addiction, compared with age- and sex-matched healthy controls with no current addictive disorder.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria For patients with FA: * Male and females ≥ 18 years old * Already in care or newly initiating care * Participating to EVALADD cohort * Current diagnosis of FA * Oral consent provided * Affiliated with French social security system or beneficiary from such system For healthy controls matched to patients with FA: * Male and females ≥ 18 years old * Oral consent provided * Affiliated with French social security system or beneficiary from such system For patients with SA: * Male ≥ 18 years old * Already in care or newly initiating care * Participating to EVALADD cohort * Current diagnosis of SA * Oral consent provided * Affiliated with French social security system or beneficiary from such system For healthy controls matched to patients with SA: * Male ≥ 18 years old * Oral consent provided * Affiliated with French social security system or beneficiary from such system Exclusion Criteria : For patients with FA: * Presence of a current diagnosis of SA * Presence of any current addictive disorder (substance \[except tobacco\] use disorders, gambling disorder, gaming disorder) * Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication) * Pregnancy or breastfeeding woman * Trusteeship or curatorship * Major cognitive impairment * Not fluent in French For patients with SA: * Presence of a current diagnosis of FA * Presence of any current addictive disorder (substance \[except tobacco\] use disorders, gambling disorder, gaming disorder) * Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication) * Trusteeship or curatorship * Major cognitive impairment * Not fluent in French For healthy controls: * Without a current diagnosis of FA * Without a current diagnosis of SA * Presence of any current addictive disorder (substance \[except tobacco\] use disorders, gambling disorder, gaming disorder) * Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication) * Pregnancy or breastfeeding woman * Trusteeship or curatorship * Major cognitive impairment * Not fluent in French

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Conditions

The condition(s) this trial relates to.

Compulsive Sexual Behavior Disorder Food Addiction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Food addiction Sexual addiction

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Nantes University Hospital

    Nantes, France

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