New transplant timing strategy may tame High-Risk blood cancers

NCT ID NCT02861417

First seen Feb 19, 2026 · Last updated May 08, 2026 · Updated 11 times

Summary

This study tests a specific schedule of chemotherapy drugs (busulfan and fludarabine) followed by a donor stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. After the transplant, a drug called cyclophosphamide is given to help prevent the donor cells from attacking the patient's body (graft-versus-host disease). The goal is to reduce the chance of cancer returning and improve survival, while managing side effects. About 204 participants are involved in this phase 2 trial.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.