New drug combo may improve stem cell transplants for blood cancer patients
NCT ID NCT02861417
First seen Feb 19, 2026 · Last updated Apr 30, 2026 · Updated 10 times
Summary
This study tests a specific timing of chemotherapy drugs (busulfan, fludarabine, and cyclophosphamide) before and after a donor stem cell transplant in 204 people with various blood cancers. The goal is to reduce the risk of the transplant failing or causing severe side effects like graft-versus-host disease. Participants receive chemotherapy to kill cancer cells and prepare the body for donor stem cells, then cyclophosphamide after transplant to help prevent the donor cells from attacking the patient's body.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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