Scientists test drug duo to boost immune attack on bladder cancer

This study is for people with muscle-invasive bladder cancer who are scheduled for surgery but cannot take standard chemotherapy beforehand. Researchers want to see how two different drug combinations affect the immune system and the tumor. One group gets an immunotherapy drug (pembrolizumab), and the other gets that same drug plus another (entinostat). The goal is to learn if these treatments make the immune system better at fighting the cancer before it is surgically removed.