Bladder cancer patients get immune drugs before surgery in new study

NCT ID NCT03978624

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 28 times

Summary

This study gave 20 people with muscle-invasive bladder cancer either pembrolizumab alone or with entinostat before their scheduled surgery. The goal was to measure changes in immune-related genes in the tumor, not to cure the disease. Participants were people who couldn't or wouldn't take standard chemotherapy.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.