Hormone blocker added to chemo for bladder cancer: early study halted

NCT ID NCT05839119

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early study tested adding a testosterone-lowering drug (degarelix) to standard chemotherapy for people with muscle-invasive bladder cancer that has testosterone receptors. Only 2 people enrolled before the study was stopped. The goal was to see if the combination could eliminate all cancer before bladder removal surgery.

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Conditions

The condition(s) this trial relates to.

bladder transitional cell carcinoma infiltrating bladder urothelial carcinoma Urinary Bladder Neoplasms urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lifespan Cancer Institute

    Providence, Rhode Island, 02912, United States