Scientists probe immune System's response to new bladder cancer drug combo

NCT ID NCT03978624

Summary

This study aims to understand how two drugs, pembrolizumab and entinostat, affect the immune system and tumor biology in patients with muscle-invasive bladder cancer. It involves 20 patients who cannot receive standard chemotherapy and are scheduled for surgery. Researchers will analyze tumor and blood samples taken before and after a short course of treatment to measure changes in immune markers.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.