New hope for lung cancer patients: experimental drug takes on chemo after standard therapy fails

NCT ID NCT06382116

First seen Nov 17, 2025 · Last updated Apr 24, 2026 · Updated 15 times

Summary

This study tests a new drug called BL-B01D1 against standard chemotherapy for people with advanced non-small cell lung cancer that has a specific EGFR mutation and has stopped responding to initial targeted therapy. About 432 adults will be randomly assigned to receive either BL-B01D1 or platinum-based chemo. The main goal is to see which treatment better delays cancer growth or death.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, China

Conditions

Explore the condition pages connected to this study.