Immune cell therapy shows promise for BK virus in transplant kids

NCT ID NCT04197596

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether specially grown immune cells (BK-specific cytotoxic T-cells) from a related donor can safely lower BK virus levels in children, teens, and young adults. Participants have BK infections that did not get better with standard treatment, often after a stem cell or organ transplant, or due to a weak immune system. The cells are given by infusion, and the study monitors for side effects and virus reduction.

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Conditions

The condition(s) this trial relates to.

BK-virus nephropathy inborn error of immunity Primary Immunodeficiency Diseases viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nationwide Children's Hosptial

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New York Medical College

    RECRUITING

    Vallhala, New York, 10595, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Email: •••••@•••••

  • Washington University

    RECRUITING

    St Louis, Missouri, 63130, United States

    Contact Email: •••••@•••••