Immune cell therapy shows promise for BK virus in transplant kids

NCT ID NCT04197596

Recruiting now Disease control Sponsor: New York Medical College Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether specially grown immune cells (BK-specific cytotoxic T-cells) from a related donor can safely lower BK virus levels in children, teens, and young adults. Participants have BK infections that did not get better with standard treatment, often after a stem cell or organ transplant, or due to a weak immune system. The cells are given by infusion, and the study monitors for side effects and virus reduction.

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Conditions

The condition(s) this trial relates to.

BK-virus nephropathy inborn error of immunity Primary Immunodeficiency Diseases viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRIMARY IMMUNE DEFICIENCY DISORDER VIRAL INFECTION

Contacts and locations

Locations

Children's Hospital of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Johns Hopkins
RECRUITING

Baltimore, Maryland, 21287, United States
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Nationwide Children's Hosptial
RECRUITING

Columbus, Ohio, 43205, United States
New York Medical College
RECRUITING

Vallhala, New York, 10595, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94158, United States
Washington University
RECRUITING

St Louis, Missouri, 63130, United States

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