New drug BIVV020 shows promise for chronic ITP in small trial

NCT ID NCT04669600

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 2a trial tested the drug BIVV020 in 12 adults with persistent or chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, raising bleeding risk. The main goal was to see if BIVV020 could help maintain a safe platelet count over time and reduce the need for emergency treatments. The study was small and open-label, meaning everyone knew they were getting the drug, so results are preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BIVV020 (SAR445088)

What this could lead to

If successful, BIVV020 could offer a new treatment option for people with chronic immune thrombocytopenia (ITP) to help maintain safe platelet levels.

What could go wrong

This was a very small, early-phase trial with only 12 participants, so results may not apply to everyone. The drug may cause side effects or not work as well in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Purpura, Thrombocytopenic, Idiopathic thrombocytopenia due to immune destruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number :2030002

    Ostrava - Poruba, 70852, Czechia

  • Investigational Site Number :2760001

    Essen, 45147, Germany

  • Investigational Site Number :5280001

    Leiden, 2333 ZA, Netherlands

  • Investigational Site Number :7240001

    Palma de Mallorca, 07120, Spain

  • Investigational Site Number :7240002

    A Coruña, A Coruña [La Coruña], 15006, Spain

  • Investigational Site Number :7240003

    Seville, 41013, Spain

  • Investigational Site Number :8260002

    London, London, City of, W12 0HS, United Kingdom

  • Investigational Site Number :8400001

    Washington D.C., District of Columbia, 20007, United States

  • Investigational Site Number :8400002

    Tamarac, Florida, 33321, United States