Mesh Match-Up: which material works best for breast reconstruction?
NCT ID NCT05449691
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing whether women and surgeons are comfortable with being randomly assigned to receive either a biological or synthetic mesh during immediate breast reconstruction after mastectomy. Sixty women will take part and be followed for six months. The results will help design a larger trial that could ultimately improve outcomes and quality of life for breast cancer patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
biological or synthetic mesh
What this could lead to
If successful, this could lead to a larger study that helps surgeons choose the best mesh for breast reconstruction, improving patient satisfaction and reducing complications.
What could go wrong
This is a small feasibility study with only 60 participants, so results may not apply to all patients. It is not designed to prove which mesh is better, only to see if a larger trial is possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Castle Hill Hospital
RECRUITINGHull, United Kingdom
Contact Email: •••••@•••••
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Nottingham City Hospital
RECRUITINGNottingham, United Kingdom
Contact Email: •••••@•••••
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University Hospitals of Derby and Burton NHS Foundation Trust
RECRUITINGDerby, DE22 3NE, United Kingdom
Contact Email: •••••@•••••
Contact
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University Hospitals of Leicester NHS Trust
RECRUITINGLeicester, United Kingdom
Contact Email: •••••@•••••
Contact
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Wycombe Hospital
RECRUITINGHigh Wycombe, United Kingdom
Contact Email: •••••@•••••