Hope for rett syndrome: new drug trial targets behavior and communication
NCT ID NCT06840496
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an oral medicine called bionetide in 210 girls and women with Rett syndrome, a rare genetic disorder. The goal is to see if bionetide improves behavior and communication compared to a placebo over 12 weeks. Participants must be 5 to 20 years old and have a confirmed MECP2 gene mutation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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Biomed Research Unit- BIO-22-VIC 3010
RECRUITINGParkville, Victoria, 3010, Australia
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Biomed Research Unit-BIO-21-VIC-3084
RECRUITINGHeidelberg West, Victoria, 3084, Australia
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Biomed Research Unit-BIO-23-NSW 2050
RECRUITINGCamperdown, New South Wales, 2050, Australia
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Biomed Research Unit-BIO-24-NSW-4101
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
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Biomed Testing Facility # BIO-01-85012
RECRUITINGPhoenix, Arizona, 85012, United States
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Biomed Testing Facility # BIO-02-94104
RECRUITINGSan Francisco, California, 94104, United States
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Biomed Testing Facility # BIO-03-95817
RECRUITINGSacramento, California, 95817, United States
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Biomed Testing Facility # BIO-04-90095
RECRUITINGLos Angeles, California, 90045, United States
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Biomed Testing Facility # BIO-05-92093
RECRUITINGLa Jolla, California, 92093, United States
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Biomed Testing Facility #BIO-06-80042
RECRUITINGAurora, Colorado, 80042, United States
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Biomed Testing Facility #BIO-07-33606
RECRUITINGTampa, Florida, 33606, United States
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Biomed Testing Facility #BIO-08-60612
RECRUITINGChicago, Illinois, 60612, United States
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Biomed Testing Facility #BIO-10-02115
RECRUITINGBoston, Massachusetts, 02115, United States
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Biomed Testing Facility #BIO-13-10467
RECRUITINGThe Bronx, New York, 10467, United States
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Biomed Testing Facility #BIO-17-19104
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Biomed Testing Facility #BIO-19-77030
RECRUITINGHouston, Texas, 77030, United States
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Biomed Testing Facility #BIO-20-98105
RECRUITINGSeattle, Washington, 98105, United States
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Maryland Locations Biomed Testing Facility #BIO-9-21205
RECRUITINGBaltimore, Maryland, 21205, United States
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More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A private facebook group may ease the emotional burden of caring for a child with rett syndrome
- Antioxidant cocktail may ease motor deficits in rett syndrome — a trial investigates
- Can robot legs help Non-Walking kids join in at school?
- Can early parent coaching help infants with rare genetic disorders thrive?
- Newborn screening study aims to catch rare diseases at birth
- Massive global registry aims to unlock secrets of rett syndrome