New biomarkers could speed up pneumonia diagnosis in ICU patients
NCT ID NCT05117125
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether certain proteins, lung bacteria, and bacterial gene patterns can help predict or diagnose pneumonia in patients on breathing machines. Researchers will measure these biomarkers in 1,000 ICU patients and compare those who develop pneumonia to those who do not. The goal is to find faster, more accurate ways to diagnose ventilator-associated pneumonia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Heparin-binding protein, Interleukin-26, lung microbiome analysis, bacterial transcriptome analysis
What this could lead to
If successful, this could lead to faster and more accurate diagnosis of ventilator-associated pneumonia, helping doctors start the right treatment sooner.
What could go wrong
This is an early-stage biomarker study, not a treatment trial. The markers may not prove accurate enough for routine use, and results may not apply to all ICU patients.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital de São Francisco Xavier
RECRUITINGLisbon, Portugal
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Karolinska University Hospital, ICU
NOT_YET_RECRUITINGSolna, Sweden
Contact
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Skåne University Hospital, Dept. of Infectious diseases
RECRUITINGLund, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Skåne university Hospital, ICU
RECRUITINGMalmö, Sweden
Contact
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Vestre Viken
RECRUITINGDrammen, 3004, Norway
Contact Phone: •••-•••-•••• Email: •••••@•••••