Heart study tests Metal-Free option for long artery blockages

NCT ID NCT06710210

Recruiting now Disease control Sponsor: University Hospital, Geneva Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to treat long, diffuse blockages in heart arteries. One method uses a temporary scaffold and drug-coated balloons that leave no permanent metal behind. The other uses standard metal stents. Researchers will check how well blood flow improves right after the procedure and at 12 months. The trial involves 150 adults with stable or unstable heart conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bioresorbable magnesium scaffold and drug-coated balloons
What this could lead to: If successful, this hybrid approach could offer a metal-free alternative to permanent stents for treating long coronary artery blockages, potentially reducing long-term complications.
What could go wrong: This is a small pilot study with only 150 participants, so results may not apply to everyone. The approach is new and may not be as effective or safe as standard stents.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE DIFFUSE CORONARY ARTERY DISEASE PERCUTANEOUS CORONARY INTERVENTION (PCI)

Contacts and locations

Locations

Basel University Hospital
RECRUITING

Basel, Switzerland
Geneva University Hospitals
RECRUITING

Geneva, Canton of Geneva, 1205, Switzerland
Zurich University Hospital
RECRUITING

Zurich, Switzerland

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