First human test of BIIB145 begins: could this be a new MS hope?

NCT ID NCT07225517

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests the safety of a new drug called BIIB145, designed to help people with multiple sclerosis (MS). Researchers will give the drug or a placebo to 104 healthy adults in three parts, checking for side effects and how the body processes it. The goal is to see if it's safe enough to test in MS patients later.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
BIIB145
What this could lead to
If this drug is safe and works well, it could lead to a new treatment for multiple sclerosis (MS).
What could go wrong
This is a very early Phase 1 study in healthy people, not MS patients. The drug may not be safe or effective in later trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • PPD Austin Clinic

    RECRUITING

    Austin, Texas, 78744, United States

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