New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT03433898

First seen Jan 04, 2026 · Last updated May 10, 2026 · Updated 15 times

Summary

This early-phase study tested two experimental drugs (BI 754091 and BI 754111) alone or together in 146 Asian patients with advanced solid tumours. The goal was to find safe doses and check for early signs of tumour shrinkage. The study is complete, but results are not yet public.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Chang Gung Memorial Hospital(Linkou)

    Taoyuan, 333, Taiwan

  • Japanese Foundation for Cancer Research

    Tokyo, Koto-ku, 135-8550, Japan

  • Kanagawa Cancer Center

    Kanagawa, Yokohama, 241-8515, Japan

  • NCKUH

    Tainan, 70403, Taiwan

  • National Cancer Center Hospital

    Tokyo, Chuo-ku, 104-0045, Japan

  • National Cancer Center Hospital East

    Chiba, Kashiwa, 277-8577, Japan

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Saitama Cancer Center

    Saitama, Kitaadachi-gun, 362-0806, Japan

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital

    Seoul, 03722, South Korea

  • Shizuoka Cancer Center

    Shizuoka, Sunto-gun, 411-8777, Japan

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

Conditions

Explore the condition pages connected to this study.