New eye drug trial hopes to tame Diabetes-Related vision loss

NCT ID NCT07553429

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study tests a new medicine called BI 3812465 for people with diabetic macular edema, a condition that causes swelling in the center of the eye and can lead to vision loss. The trial has two parts: first, a small group gets low to high doses to check safety, then a larger group is randomly assigned to different doses. Participants receive three injections into the eye over several months and are monitored for side effects and eye health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DIABETIC MACULAR EDEMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Associated Retina Consultants, Ltd.

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85020, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Austin Clinical Research, LLC

    RECRUITING

    Austin, Texas, 78750, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bay Area Retina Associates - Walnut Creek

    RECRUITING

    Walnut Creek, California, 94598, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • California Retina Consultants-Oxnard-70187

    NOT_YET_RECRUITING

    Oxnard, California, 93036, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • East Florida Eye Institute

    RECRUITING

    Stuart, Florida, 34994, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emanuelli Research & Development Center

    RECRUITING

    Arecibo, 00612, Puerto Rico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emerson Clinical Research Institute

    RECRUITING

    Falls Church, Virginia, 22042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • EyeHealth Northwest

    RECRUITING

    Portland, Oregon, 97225, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Florida Retina Consultants

    NOT_YET_RECRUITING

    Lakeland, Florida, 33805, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Florida Retina Institute Wildwood

    NOT_YET_RECRUITING

    Wildwood, Florida, 34785, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Global Research Management

    RECRUITING

    Glendale, California, 91204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical Center Ophthalmology Associates

    RECRUITING

    San Antonio, Texas, 78240, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • North Carolina Retina Associates

    NOT_YET_RECRUITING

    Wake Forest, North Carolina, 27587, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ophthalmic Consultants of Long Island

    NOT_YET_RECRUITING

    Oceanside, New York, 11572, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Red River Research Partners, LLC

    RECRUITING

    Fargo, North Dakota, 58103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Research Network Arizona

    RECRUITING

    Scottsdale, Arizona, 85255, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Associates of Southern California

    NOT_YET_RECRUITING

    Huntington Beach, California, 92647, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Texas - San Antonio Medical Center

    NOT_YET_RECRUITING

    San Antonio, Texas, 78240, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Texas-Bellaire-67493

    NOT_YET_RECRUITING

    Bellaire, Texas, 77401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Consultants of Texas-The Woodlands-67575

    NOT_YET_RECRUITING

    The Woodlands, Texas, 77384, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Group of Florida - Fort Myers Retina Center

    RECRUITING

    Fort Myers, Florida, 33912, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina Group of New England, PC

    NOT_YET_RECRUITING

    Waterford, Connecticut, 06385, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retina-Vitreous Associates Medical Group

    NOT_YET_RECRUITING

    Beverly Hills, California, 90211, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Retinal Consultants Medical Group

    NOT_YET_RECRUITING

    Sacramento, California, 95825, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Strategic Clinical Research Group

    RECRUITING

    Willow Park, Texas, 76087, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tennessee Retina

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Valley Retina Institute, PA

    RECRUITING

    McAllen, Texas, 78503, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Verum Research, LLC

    RECRUITING

    Eugene, Oregon, 97401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Win Retina

    RECRUITING

    Arcadia, California, 91006, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.