Liver function may change drug levels in new lung treatment study

NCT ID NCT07023354

First seen Nov 15, 2025 · Last updated May 12, 2026 · Updated 15 times

Summary

This study looks at how the body processes a new medicine called BI 1291583 in people with and without liver problems. The drug is being developed for bronchiectasis, a chronic lung disease. About 32 adults will take a single dose of the drug, and researchers will measure its levels in the blood over time. The goal is to understand if liver impairment changes how the drug works, which helps guide safe dosing for future patients.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • American Research Corporation at the Texas Liver Institute

    RECRUITING

    San Antonio, Texas, 78215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orlando Clinical Research Center

    RECRUITING

    Orlando, Florida, 32809, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tranquil Clinical Research

    COMPLETED

    Houston, Texas, 77598, United States

Conditions

Explore the condition pages connected to this study.