New drug shows promise in taming epileptic brain signals

NCT ID NCT07125261

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This early-phase study tests whether BHV-7000, a drug that activates potassium channels, can reduce abnormal electrical activity in the brains of people with focal epilepsy who have an implanted RNS device. Five participants will take the drug for 4 weeks, and their brain recordings will be compared to a 90-day baseline and a 4-week withdrawal period. The goal is to see if the drug can calm seizure-related patterns without requiring long-term medication changes.

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Contacts and locations

Locations

  • Yale Comprehensive Epilepsy Center

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.