New hope for kids with rare swelling disorder: daily pill may stop attacks
NCT ID NCT05453968
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a daily medication called berotralstat in 29 children aged 2 to under 12 who have hereditary angioedema (HAE), a condition that causes sudden, painful swelling attacks. The goal is to find the right dose based on weight and to check if it is safe and effective at preventing these attacks. Participants take the pill daily and are monitored for side effects and attack frequency.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Investigative Site #1
Vienna, Ontario, Austria
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Investigative Site #1
Ottawa, Ontario, Canada
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Investigative Site #1
Paris, France
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Investigative Site #1
Berlin, Germany
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Investigative Site #1
Tel Aviv, Israel
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Investigative Site #1
Padova, Italy
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Investigative Site #1
Krakow, Poland
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Investigative Site #1
Sângeorgiu de Mureş, Romania
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Investigative Site #1
Madrid, Spain
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Investigative Site #1
Bristol, United Kingdom
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Investigative Site #2
Marseille, France
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Investigative Site #2
Frankfurt, Germany
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Investigative Site #2
Haifa, Israel
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Investigative Site #2
Málaga, Spain
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Investigative Site #3
Grenoble, France