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Can a supplement and quick sprints boost your mood and immune system?

NCT ID NCT07480018

Knowledge-focused Sponsor: University of Northern Colorado Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking berberine (a natural supplement) or doing short, intense sprint workouts for two weeks can improve mental health, energy, sleep, and immune cell function. Forty adults with mild depression, anxiety, or stress took part. The goal was to see if these simple interventions could help wellbeing and reduce inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males and Females * Aged 18-45 * DASS-21 subscale scores indicating "Mild" or greater category for Depression ≥ 10, Anxiety ≥ 7, and Stress ≥ 11 Exclusion Criteria: * Regular berberine intake in the last 2 months * Performs SIT regularly in the last month * Pregnant or planning to become pregnant * Chronic use of anti-inflammatory medication or medications that affect liver metabolism * Prior history of chronic conditions such as Cardiovascular Disease, Diabetes, and Cancer * Severe and untreated anxiety or depression * Severe Peanut Allergies * Any contraindications to performing high intensity exercise

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Conditions

The condition(s) this trial relates to.

Inflammation Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anaerobic power Berberine Inflammation biomarkers Monocyte function Sprint training Wellbeing

Contacts and locations

Locations

  • University of Northern Colorado

    Greeley, Colorado, 80631, United States

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