New hope for kids with rare blood disorders: benralizumab trial launches

NCT ID NCT06512883

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This Phase 3 trial tests the drug benralizumab (Fasenra) in children aged 6 to 17 with two rare eosinophilic diseases: EGPA and HES. The study aims to see if the drug is safe, how it works in the body, and whether it can help control the disease. Fourteen children will receive injections every 4 weeks, with researchers monitoring side effects and remission rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

benralizumab (Fasenra)

What this could lead to

If successful, this could provide a treatment option to control eosinophilic diseases in children, reducing symptoms and reliance on steroids.

What could go wrong

This is a small, open-label trial with only 14 participants, so results may not apply broadly. Side effects or lack of efficacy are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

eosinophilic granulomatosis with polyangiitis hypereosinophilic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Research Site

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45229, United States

  • Research Site

    RECRUITING

    Highland Hills, Ohio, 44106-2624, United States

  • Research Site

    RECRUITING

    São Paulo, 01232-010, Brazil

  • Research Site

    RECRUITING

    Toronto, Ontario, M5G1X8, Canada

  • Research Site

    NOT_YET_RECRUITING

    Lille, 59037, France

  • Research Site

    NOT_YET_RECRUITING

    Montpellier, 34295, France

  • Research Site

    NOT_YET_RECRUITING

    Ahmedabad, 380052, India

  • Research Site

    NOT_YET_RECRUITING

    Petah Tikva, 49202, Israel

  • Research Site

    RECRUITING

    Guadalajara, 44620, Mexico

  • Research Site

    NOT_YET_RECRUITING

    Rotterdam, 3015 GD, Netherlands

  • Research Site

    NOT_YET_RECRUITING

    Kielce, 25-734, Poland

  • Research Site

    NOT_YET_RECRUITING

    Warsaw, 04-730, Poland

  • Research Site

    RECRUITING

    Altındağ, 06230, Turkey (Türkiye)

  • Research Site

    RECRUITING

    Istanbul, 34093, Turkey (Türkiye)