Vitamin B1 derivative trial aims to put brakes on Alzheimer's decline

NCT ID NCT06223360

Summary

This study is testing whether a form of vitamin B1 called benfotiamine can slow down the worsening of memory and daily function in people with early Alzheimer's disease. Over 400 participants will take either the study drug or a placebo for 18 months to see if it is safe and effective. The goal is to find a new treatment that could help control the progression of the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AMC Research LLC, dba Flourish Research

    RECRUITING

    Matthews, North Carolina, 28105, United States

  • Albany Medical College

    RECRUITING

    Albany, New York, 12208, United States

  • Banner Sun Health Research Institute

    RECRUITING

    Sun City, Arizona, 85351, United States

  • Blue Medical Research Inc.

    RECRUITING

    Miami, Florida, 33144, United States

  • Brain Matters Research

    RECRUITING

    Delray Beach, Florida, 33445, United States

  • Brain Matters Research (Kane Center)

    RECRUITING

    Stuart, Florida, 34997, United States

  • Brainstorm Research

    RECRUITING

    Miami, Florida, 33176, United States

  • CCM Clinical Research Group, LLC

    RECRUITING

    Miami, Florida, 33133, United States

  • Case Western Reserve University

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • Cedars Sinai, Los Angeles

    RECRUITING

    Los Angeles, California, 90048, United States

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • Conquest Research

    RECRUITING

    Winter Park, Florida, 32789, United States

  • Dent Neurologic Institute

    RECRUITING

    Amherst, New York, 14226, United States

  • Emory University Goizueta Alzheimer's Disease Research Center(GADRC)

    RECRUITING

    Atlanta, Georgia, 30329, United States

  • Froedtert and Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Geisinger Memory and Cognition Center

    RECRUITING

    Wilkes-Barre, Pennsylvania, 18711, United States

  • Gonzalez MD & Aswad MD Health Services

    RECRUITING

    Miami, Florida, 33135, United States

  • Integrative Clinical Trials

    RECRUITING

    Brooklyn, New York, 11229, United States

  • JEM Research Institute

    RECRUITING

    Atlantis, Florida, 33462, United States

  • KCA Neurology

    RECRUITING

    Tennessee City, Tennessee, 37067, United States

  • MedVadis Research

    RECRUITING

    Waltham, Massachusetts, 02451, United States

  • Miami Jewish Health

    RECRUITING

    Miami, Florida, 33137, United States

  • Mount Sinai School of Medicine

    RECRUITING

    New York, New York, 10029, United States

  • Nathan Kline Institute for Psychiatric Research

    RECRUITING

    New York, New York, 10962, United States

  • Neuropsychiatric Research Center of Southwest Florida

    RECRUITING

    Fort Myers, Florida, 33912, United States

  • Northwestern University Feinberg School of Medicine

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43221, United States

  • Oregon Health & Science University (OHSU)

    RECRUITING

    Portland, Oregon, 97239, United States

  • Pacific Research Network

    TERMINATED

    Lemon Grove, California, 91945, United States

  • Perseverance Research Center, LLC

    RECRUITING

    Scottsdale, Arizona, 85253, United States

  • Ralph H. Johnson VA Health Care System

    RECRUITING

    Charleston, South Carolina, 29401, United States

  • Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

  • Rutgers, Robert Wood Johnson Medical School

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • SUNY Upstate Medical University

    RECRUITING

    Syracuse, New York, 13210, United States

  • Sandhill Research, LLC d/b/a Accel Research Sites

    RECRUITING

    Decatur, Georgia, 30030, United States

  • Southern Illinois University

    RECRUITING

    Springfield, Illinois, 62702, United States

  • St. Joseph's Hospital and Medical Center/Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • Syrentis Clinical Research

    RECRUITING

    Santa Ana, California, 92705, United States

  • The Neuron Clinic

    RECRUITING

    Chula Vista, California, 91910, United States

  • University of California, Irvine

    RECRUITING

    Irvine, California, 92697, United States

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40504, United States

  • University of Michigan, Ann Arbor

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of North Texas Health Science Center

    RECRUITING

    Fort Worth, Texas, 76107, United States

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90033, United States

  • Weill Cornell Medical College

    RECRUITING

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.