Can shrinking the radiation zone in brain cancer improve quality of life?

NCT ID NCT06719440

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 30 times

Summary

This study is for people with glioblastoma, an aggressive brain cancer. The standard treatment includes radiation to the tumor plus a safety margin, which can damage healthy brain tissue and cause side effects. The BELGICA trial tests whether using a smaller radiation area can reduce side effects and improve quality of life without shortening survival. About 347 participants will be randomly assigned to receive either standard or reduced-volume radiation, along with chemotherapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • AZ Delta

    RECRUITING

    Roeselare, 8800, Belgium

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  • AZ Groeninge

    RECRUITING

    Kortrijk, 8500, Belgium

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  • AZ Sint Jan

    RECRUITING

    Bruges, 8000, Belgium

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  • AZ Sint Maarten

    RECRUITING

    Mechelen, 2800, Belgium

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  • AZ Sint-Lucas

    RECRUITING

    Ghent, 9000, Belgium

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  • CH Mouscron

    NOT_YET_RECRUITING

    Mouscron, 7700, Belgium

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  • CHR Verviers

    RECRUITING

    Verviers, 4800, Belgium

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  • CHU Liège

    RECRUITING

    Liège, 4000, Belgium

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  • CHU UCL Namur - Sainte Elisabeth

    RECRUITING

    Namur, 5000, Belgium

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  • Chu Helora

    RECRUITING

    La Louvière, 7100, Belgium

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  • Cliniques de l'Europe

    RECRUITING

    Uccle, 1180, Belgium

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  • Cliniques universitaires Saint-Luc

    RECRUITING

    Brussels, 1200, Belgium

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  • EpiCURA

    RECRUITING

    Baudour, 7331, Belgium

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  • Grand Hôpital de Charleroi

    RECRUITING

    Gilly, 6060, Belgium

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  • Hôpital André Vésale - HUmani

    RECRUITING

    Montigny-le-Tilleul, 6110, Belgium

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  • Institut Jules Bordet

    NOT_YET_RECRUITING

    Brussels, 1070, Belgium

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  • JESSA Ziekenhuis

    RECRUITING

    Hasselt, 3500, Belgium

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  • Olv Azorg

    NOT_YET_RECRUITING

    Aalst, 9300, Belgium

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  • UZ Brussel

    NOT_YET_RECRUITING

    Brussels, 1090, Belgium

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  • UZ Gent

    NOT_YET_RECRUITING

    Ghent, 9000, Belgium

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  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

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  • ZAS Augustinus

    RECRUITING

    Wilrijk, 2610, Belgium

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  • Ziekenhuis Oost-Limburg (ZOL)

    RECRUITING

    Genk, 3600, Belgium

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Conditions

Explore the condition pages connected to this study.