Heart transplant patients may soon avoid Long-Term kidney damage

NCT ID NCT06478017

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests whether a drug called belatacept can safely replace the standard anti-rejection drug tacrolimus in heart transplant patients. The goal is to prevent organ rejection while reducing the kidney damage often caused by tacrolimus. About 66 heart transplant recipients will be randomly assigned to receive either standard care or belatacept with a gradual reduction of tacrolimus over 9 months. Researchers will monitor for rejection, kidney function, and survival for 18 months after transplant.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars Sinai Heart Institute/ Cedars Sinai Medical (Site # 71146)

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health (Site # 71177)

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Luke's Hospital of Kansas City

    RECRUITING

    Kansas City, Missouri, 64111, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tampa General Hospital (Site # 71150)

    RECRUITING

    Tampa, Florida, 33606, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah Medical Center (Site # 71126)

    RECRUITING

    Salt Lake City, Utah, 84132, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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