New combo therapy shows promise for Hard-to-Treat myeloma

NCT ID NCT07084896

First seen May 11, 2026 · Last updated May 11, 2026

Summary

This study is for people with multiple myeloma that has come back or stopped responding to at least three prior treatments. It tests a combination of two drugs—belantamab mafodotin and nirogacestat—to see if they are safe and can shrink or control the cancer. About 106 adults will take part, and the goal is to find the best dose and measure how many patients respond.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • 238995

    Atlanta, Georgia, 30322, United States

  • 239015

    Madison, Wisconsin, 53792, United States

  • 240593

    Boston, Massachusetts, 02215, United States

  • 251164

    Grand Rapids, Michigan, 49546, United States

  • GSK Investigational Site

    Fitzroy, Victoria, 3065, Australia

  • GSK Investigational Site

    Vancouver, British Columbia, V5Z1M9, Canada

  • GSK Investigational Site

    Halifax, Nova Scotia, B3H 1V7, Canada

  • GSK Investigational Site

    Lille, 59037, France

  • GSK Investigational Site

    Villejuif, 94805, France

  • GSK Investigational Site

    Frankfurt, 60590, Germany

  • GSK Investigational Site

    Kiel, 24105, Germany

  • GSK Investigational Site

    Leipzig, 04103, Germany

  • GSK Investigational Site

    Athens, 11528, Greece

  • GSK Investigational Site

    Utrecht, 3584 CX, Netherlands

  • GSK Investigational Site

    Oslo, 0450, Norway

  • GSK Investigational Site

    Katowice, 40-519, Poland

  • GSK Investigational Site

    Lodz, 93-513, Poland

  • GSK Investigational Site

    Lublin, 20-081, Poland

  • GSK Investigational Site

    Moscow, 125284, Russia

  • GSK Investigational Site

    Incheon, 21565, South Korea

  • GSK Investigational Site

    Seoul, 06351, South Korea

  • GSK Investigational Site

    Seoul, 06591, South Korea

  • GSK Investigational Site

    Ulsan, 44033, South Korea

  • GSK Investigational Site

    Badalona, 08916, Spain

  • GSK Investigational Site

    Madrid, 28041, Spain

  • GSK Investigational Site

    Madrid, 31008, Spain

  • GSK Investigational Site

    Pozuelo de AlarcOn Madr, 28223, Spain

  • GSK Investigational Site

    Falun, SE-791 82, Sweden

  • GSK Investigational Site

    Stockholm, SE-141 86, Sweden

Conditions

Explore the condition pages connected to this study.