New combo therapy aims to stop daytime accidents in kids

NCT ID NCT06551246

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a combination of two drugs (solifenacin and mirabegron) at low doses works better than a high dose of either drug alone for children aged 5 to 14 with daytime wetting. About 236 children who did not fully respond to low-dose single drugs will be randomly assigned to one of four treatment groups for 18 weeks. The goal is to reduce the number of wet days per week.

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Conditions

The condition(s) this trial relates to.

Diurnal Enuresis enuresis overactive bladder Urinary Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Pediatric and Adolescent Medicine, Aalborg University Hospital

    RECRUITING

    Aalborg, Aalborg, 9000, Denmark

  • Department of Pediatric and Adolescent Medicine, Aarhus University Hospital

    RECRUITING

    Aarhus, Aarhus N, 8200, Denmark

  • Department of Pediatric and Adolescent Medicine, Gødstrup Hospital

    RECRUITING

    Herning, Herning, 7400, Denmark

  • Department of Pediatric and Adolescent Medicine, Kolding Hospital

    RECRUITING

    Kolding, Kolding, 6000, Denmark

  • Department of Pediatric and Adolescent medicine, Esbjerg Hospital

    RECRUITING

    Esbjerg, Esbjerg, 6700, Denmark

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