Can a simple infusion save transplanted kidneys from a stealthy virus?
NCT ID NCT05325008
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether reducing anti-rejection drugs, with or without an extra treatment called IVIG, can better control BK virus in kidney transplant patients. BK virus can damage the new kidney and lead to transplant failure. About 280 adults and children who have a kidney or kidney-pancreas transplant and a high level of BK virus will take part. The goal is to find the best way to protect the kidney while managing the virus.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Canberra Hospital
RECRUITINGCanberra, Australian Capital Territory, 2605, Australia
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Flinders Medical Centre
RECRUITINGAdelaide, South Australia, 5042, Australia
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John Hunter Hospital
RECRUITINGNew Lambton Heights, New South Wales, 2305, Australia
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Monash Health
RECRUITINGMelbourne, Victoria, 3168, Australia
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Perth Children's Hospital
RECRUITINGPerth, Western Australia, 6009, Australia
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Prince of Wales Hospital
RECRUITINGRandwick, New South Wales, 2031, Australia
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Princess Alexandra Hospital
RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Queensland Children's Hospital
RECRUITINGBrisbane, Queensland, 4101, Australia
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Royal Prince Alfred Hospital
RECRUITINGSydney, New South Wales, 2050, Australia
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Sir Charles Gairdner Hospital
RECRUITINGPerth, Western Australia, 6009, Australia
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The Childrens Hospital Westmead
RECRUITINGSydney, New South Wales, 2145, Australia
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Townsville University Hospital
RECRUITINGTownsville, Queensland, 4814, Australia
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Western Sydney Local Health District (Westmead Hospital)
RECRUITINGWestmead, New South Wales, 2145, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Transplant breakdown? new study checks organ fluid for hidden germs
- Kidney transplant patients' immune response to common virus tracked after drug switch
- Immune cells may predict CMV relapse in kidney transplant patients
- Harmless virus levels may predict transplant complications
- Kidney transplant virus filter trial pulled before start
- New blood test may help protect kids from post-transplant infection