New drug aims to tame brain swelling after bleeding stroke

NCT ID NCT05020535

Ongoing Disease control Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jan 06, 2026 · Last updated Apr 30, 2026 · Updated 12 times

Summary

This study tests a new drug called MW189 in 120 people who have had a brain bleed (intracerebral hemorrhage). The goal is to see if the drug is safe and can reduce brain swelling, which often causes further damage. Participants receive the drug within 24 hours of their stroke and are monitored for side effects and survival.

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Contacts and locations

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Locations

Cleveland Clinic Florida

Stuart, Florida, 34994, United States
Johns Hopkins Hospital

Baltimore, Maryland, 21287, United States
New York University Grossman School of Medicine

Brooklyn, New York, 11220, United States
Stanford University

Palo Alto, California, 94304, United States
University of Alabama Birmingham

Birmingham, Alabama, 35294, United States
University of Cincinnati

Cincinnati, Ohio, 45219, United States
University of Kentucky

Lexington, Kentucky, 40536, United States
University of New Mexico

Albuquerque, New Mexico, 87131, United States
University of Texas Houston

Houston, Texas, 77030, United States
University of Texas San Antonio

San Antonio, Texas, 78229, United States
Yale New Haven Hospital

New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.

INTRACEREBRAL HEMORRHAGE