New pill targets Tough-to-Treat cancers in brain and lungs

NCT ID NCT05256290

Summary

This study is testing an oral medication called BDTX-1535 for adults with advanced non-small cell lung cancer or glioblastoma (a type of brain tumor) that have specific genetic changes. The goal is to find the safest and most effective dose and see if the drug can shrink tumors, especially those that have spread to the brain. Participants will take the pill daily in 21-day cycles.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • City of Hope Huntington Beach

    Huntington Beach, California, 92648, United States

  • City of Hope Orange County Lennar Foundation Cancer Center

    Irvine, California, 92618, United States

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Fred Hutchinson Cancer Center/University of Washington

    Seattle, Washington, 98109, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Johns Hopkins Bayview Medical Center

    Baltimore, Maryland, 21224, United States

  • Mayo Clinic- Jacksonville

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic- Rochester

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10021, United States

  • Miami Cancer Institute - Baptist Health South Florida

    Miami, Florida, 33176, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Next Ocology

    Fairfax, Virginia, 22031, United States

  • Robert H. Lurie Comprehensive Cancer Center at Northwestern University

    Chicago, Illinois, 60611, United States

  • Sibley Memorial Hospital Johns Hopkins Medicine

    Washington D.C., District of Columbia, 20016, United States

  • Siteman Cancer Center

    St Louis, Missouri, 63110, United States

  • Tennessee Oncology

    Nashville, Tennessee, 37203, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UHP- University of Hawaii Cancer Center

    Honolulu, Hawaii, 96813, United States

  • UNC Hospitals - Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27514, United States

  • University of Alabama

    Birmingham, Alabama, 35294, United States

  • University of Kansas Cancer Center

    Fairway, Kansas, 66205, United States

  • University of Pittsburgh Medical Center - Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.