New hope for young hemophilia patients: safer, fewer injections on the horizon

NCT ID NCT05147662

First seen Jan 04, 2026 · Last updated May 02, 2026 · Updated 20 times

Summary

This study looked at the safety of BAY 94-9027 (Jivi) in 36 children aged 7 to 12 with severe hemophilia A. The medicine is a longer-lasting clotting factor given as an injection to prevent and treat bleeding. Researchers monitored for allergic reactions and whether the drug stopped working well, especially during the first four doses. The goal is to provide a safer, more convenient treatment option for this age group.

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Contacts and locations

Locations

  • Acibadem Adana Hastanesi, Çocuk Sagligi ve Hastaliklari, Çocuk Hematoloji-Onkoloji Bölümü

    Adana, 01130, Turkey (Türkiye)

  • Akdeniz Üniversitesi Tip Fakültesi Çocuk Sagligi ve Hastaliklari Anabilim Dali Çocuk Hematoloji ve Onkoloji Bilim Dali

    Antalya, 07059, Turkey (Türkiye)

  • Arnold Palmer Hospital for Children

    Orlando, Florida, 32806, United States

  • Ege Üniversitesi Tip Fakültesi, Çocuk Sagligi ve Hastaliklari Anabilim Dali, Çocuk Hematoloji Bilim Dali

    Izmir, 35100, Turkey (Türkiye)

  • Gaziantep Üniversitesi Tip Fakültesi, Sahinbey Arastirma Ve Uygulama Hastanesi, Çocuk Hematoloji ve Onkoloji Bilim Dali

    Gaziantep, 27100, Turkey (Türkiye)

  • HEMORIO

    Rio de Janeiro, Rio de Janeiro, 20211-030, Brazil

  • Hacettepe Üniversitesi Tip Fakültesi, Hacettepe Ihsan Dogramaci Çocuk Hastanesi,

    Ankara, 06230, Turkey (Türkiye)

  • Hosp Clínicas Facult. Med. de Ribeirão Preto / USP

    Ribeirão Preto, São Paulo, 14051-140, Brazil

  • Hospital das Clínicas de Campinas - UNICAMP

    Campinas, São Paulo, 13083-878, Brazil

  • Hospital de Niños Sor María Ludovica

    La Plata, Buenos Aires, 1900, Argentina

  • Instituo Hematología Arbesú

    Godoy Cruz, Mendoza Province, 5501, Argentina

  • Instituto de Hematología Dr. Rubén Dávoli

    Rosario, Santa Fe Province, S2000CKF, Argentina

  • Irmandadade da Santa Casa de Misericordia de Sao Paulo (iSANTACASA)

    São Paulo, São Paulo, 01223-001, Brazil

  • McMaster Children's Hospital

    Hamilton, Ontario, L8N 3Z5, Canada

  • OUS Rikshospitalet Klinisk Forskningspost Barn

    Oslo, 372, Norway

  • Ondokuz Mayis Üniversitesi Tip Fakültesi, Saglik Uygulama ve Arastirma Merkezi, Çocuk Sagligi ve Hastaliklari Anabilim Dali

    Samsun, 55200, Turkey (Türkiye)

  • Ospedale Pediatrico Bambino Gesù - Oncoematologia, Trapianto Emopoietico e Terapie Cellulari

    Roma (RM), Lazio, 00165, Italy

Conditions

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