New hope for chronic hives: barzolvolimab shows promise in Long-Term trial

NCT ID NCT07256392

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 4 times

Summary

This study looks at the long-term safety and effectiveness of barzolvolimab in adults with chronic spontaneous urticaria (CSU), a condition causing frequent hives and itching. Participants have already completed earlier phase 3 trials. The goal is to see how well the drug controls symptoms over time and to provide continued access to treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • About Allergy

    Pretoria, Gauteng, 0181, South Africa

  • Advanced Clinical Research Institute (ACRI) - Florida

    Tampa, Florida, 33607, United States

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Alina Clinical Trials LLC

    Dallas, Texas, 75225, United States

  • Allergy Associates of Utah

    Sandy City, Utah, 84093, United States

  • Allergy and Asthma Associates of Southern California - Laguna Niguel - CRN

    Laguna Niguel, California, 92677, United States

  • Aprillus Asistencia e Investigacion de Arcis Salud SRL

    CABA, Buenos Aires F.D., 1406, Argentina

  • Auni Allergy

    Findlay, Ohio, 45840, United States

  • Azienda Ospedaliera Ordine Mauriziano di Torino

    Torino, 20128, Italy

  • Bexley Dermatology Research

    Bexley, Ohio, 43209, United States

  • CHRU Nantes Hôtel Dieu

    Nantes, 44093, France

  • CHU de Nice-Hôpital L'Archet

    Nice, 06202, France

  • Cahaba Dermatology & Skin Health Center, LLC

    Birmingham, Alabama, 35244, United States

  • Center for Dermatology & Plastic Surgery - Avacare

    Scottsdale, Arizona, 85260, United States

  • Centricity Research Columbus Dermatology

    Columbus, Georgia, 31904, United States

  • Centro Internacional de Estudios Clinicos (CIEC)

    Recoleta, 8420383, Chile

  • Centro Respiratorio Infantil

    Rosario, Sante Fe, 2000, Argentina

  • Centrum Badan Klinicznych PI-House sp. z o.o.

    Gdansk, 80-546, Poland

  • Centrum Medyczne Pratia Poznan

    Poznan, 60-185, Poland

  • Centrum Nowoczesnych Terapii Dobry Lekarz Sp. z o.o.

    Krakow, 31-011, Poland

  • Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital

    Kaohsiung City, 833, Taiwan

  • China Medical University Hospital

    Taichung, 404, Taiwan

  • Cityclinic Przychodnia Lekarsko Psychologiczna Matusiak Spółka Partnerska

    Wroclaw, 50-566, Poland

  • Clinica Mayo de Urgencias

    San Miguel de Tucumán, Tucumán Province, 4000, Argentina

  • Clinical Partners LLC

    Johnston, Rhode Island, 02919, United States

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Conexa Investigación Clínica S.A.

    CABA, Buenos Aires F.D., 1012, Argentina

  • Cornerstone Dermatology

    Coorparoo, QSL, 4151, Australia

  • Deluxe Health Center

    Miami Lakes, Florida, 33014, United States

  • Dermacross Clinica Dermatologica

    Vitacura, 7630000, Chile

  • Dermatology Research Associates

    Los Angeles, California, 90045, United States

  • Direct Helpers Research Center

    Hialeah, Florida, 33012, United States

  • Dolphin Medical Research

    Doral, Florida, 33172, United States

  • Encore Medical Research of Boynton Beach LLC

    Boynton Beach, Florida, 33436, United States

  • Endeavor Health

    Skokie, Illinois, 60026, United States

  • Enroll SpA - Dr. Manuel Barros Borgono

    Providencia, 7500000, Chile

  • EuroMediCare Szpital Specjalistyczny z Przychodnia we Wroclawiu

    Wroclaw, 54-144, Poland

  • Evidence Based Medical Educator Inc.

    Toronto, Ontario, M5G1E2, Canada

  • GCP, Global Clinical Professionals

    St. Petersburg, Florida, 33705, United States

  • Ginemedica Sp. z o.o.

    Wroclaw, 50-414, Poland

  • Global Clinical Trials (Pty) Ltd - Pretoria

    Pretoria, Gauteng, 0157, South Africa

  • Hanyang University Seoul Hospital

    Seoul, 4763, South Korea

  • Hospital A. Syggros

    Athens, 16121, Greece

  • Hospital Clinico San Carlos - Lopez Bran

    Madrid, 28040, Spain

  • Hospital General Universitario Dr. Balmis

    Alicante, 03010, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 8035, Spain

  • Hospital Universitario de La Plana

    Villarreal de Huerva, 12540, Spain

  • Hospital del Mar

    Barcelona, 8003, Spain

  • Institute for Asthma and Allergy

    Wheaton, Maryland, 20902, United States

  • Instituto Médico de la Fundación Estudios Clínicos

    Rosario, Sante Fe, S2000DEJ, Argentina

  • Instituto de Especialidades de la Salud Rosario - Clínica del Tórax

    Rosario, Sante Fe, 2000, Argentina

  • Joel Liem Medicine Professional Corporation

    Windsor, Ontario, N8X 2G1, Canada

  • John Hopkins University

    Baltimore, Maryland, 21224, United States

  • Kaohsiung Veterans General Hospital

    Kaohsiung City, 813414, Taiwan

  • Kern Research

    Bakersfield, California, 93301, United States

  • Klinika Ambroziak Dermatologia

    Warsaw, 02-953, Poland

  • LA Universal Research Center, Inc.

    Los Angeles, California, 90057, United States

  • Lima's Excellence In Allergy And Dermatology Research (Leader) Inc.

    Hamilton, Ontario, L8L 3C3, Canada

  • Lynderm Research Inc

    Markham, Ontario, L3P 1X3, Canada

  • MICS Centrum Medyczne Toruń

    Torun, 87-100, Poland

  • MacKay Memorial Hospital

    Taipei, 10449, Taiwan

  • Markowitz Medical PLLC dba OptiSkin Medical

    New York, New York, 10128, United States

  • Medical Center Hera EOOD

    Sofia, 1510, Bulgaria

  • Medical Center Iskar EOOD

    Sofia, 1000, Bulgaria

  • Medical Center Medtech Services EOOD

    Haskovo, 6304, Bulgaria

  • Medical Center Pulmovision

    Sofia, 1756, Bulgaria

  • Medical Research of Arizona

    Scottsdale, Arizona, 85251, United States

  • Medizinisches Versorgungszentrum DermaKiel GmbH

    Kiel, Schleswig-Holstein, 24148, Germany

  • Michigan Center for Research Co., LLC

    Clarkston, Michigan, 48346, United States

  • Midwest Clinical Research

    St Louis, Missouri, 63141, United States

  • Montana Medical Research, Inc.

    Missoula, Montana, 59808, United States

  • National Taiwan University Hospital

    Taipei, 10048, Taiwan

  • National Taiwan University Hospital - Hsin-Chu Branch

    Hsinchu, 300, Taiwan

  • Newtown Clinical Research Centre

    Newtown, Gauteng, 2001, South Africa

  • Outpatient Clinic for IP for Specialized Outpatient Medical Care in Allergology-Dr.Cholak

    Razgrad, 7200, Bulgaria

  • Portland Allergy and Asthma

    Clackamas, Oregon, 97015, United States

  • ProDerma

    Dülmen, North Rhine-Westphalia, 48249, Germany

  • Rainey & Finklea San Antonio (RFSA) Dermatology

    San Antonio, Texas, 78213, United States

  • Respiratory Medicine Research Institute of Michigan PLC

    Ypsilanti, Michigan, 48197, United States

  • Sarasota Clinical Research

    Sarasota, Florida, 34239, United States

  • Seoul National University Hospital

    Seoul, 3080, South Korea

  • Synapta Clinical Research Centre

    Durban, KwaZulu-Natal, 4001, South Africa

  • Synexus Polska Sp. z o.o. Oddzial w Katowicach

    Katowice, 40-040, Poland

  • Thammasat University Hospital

    Khlong Luang, 12120, Thailand

  • The Alfred Hospital - Kern

    Melbourne, Victoria, 3004, Australia

  • The South Bend Clinic - Avacare

    South Bend, Indiana, 46617, United States

  • Toledo Institute for Clinical Research

    Toledo, Ohio, 43617, United States

  • ULS da Região de Aveiro, EPE - Hospital Infante D. Pedro

    Aveiro, 3814-501, Portugal

  • ULS de Coimbra, EPE - Hospitais da Universidade de Coimbra

    Coimbra, 3004-561, Portugal

  • University General Hospital ''ATTIKON'' - General Hospital of West Attica H AGIA VARVARA

    Chaïdári, Attica, 12462, Greece

  • University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov EAD

    Sofia, 1606, Bulgaria

  • University of Cape Town Lung Institute (UCTLI)

    Mowbray, Western Cape, 7700, South Africa

  • VIDA Dermatology

    Edmonton, Alberta, T6H 4J8, Canada

  • Velocity Clinical Research, North London

    North Finchley, N12 8BU, United Kingdom

  • Western Sky Medical Research

    El Paso, Texas, 79912, United States

  • Worthwhile Clinical Trials

    Benoni, Gauteng, 1501, South Africa

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