New hope for chronic hives: barzolvolimab shows promise in Long-Term trial

NCT ID NCT07256392

ENROLLING_BY_INVITATION Disease control Sponsor: Celldex Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study looks at the long-term safety and effectiveness of barzolvolimab in adults with chronic spontaneous urticaria (CSU), a condition causing frequent hives and itching. Participants have already completed earlier phase 3 trials. The goal is to see how well the drug controls symptoms over time and to provide continued access to treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic idiopathic urticaria Chronic Urticaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC SPONTANEOUS URTICARIA

Contacts and locations

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Locations

About Allergy

Pretoria, Gauteng, 0181, South Africa
Advanced Clinical Research Institute (ACRI) - Florida

Tampa, Florida, 33607, United States
Ajou University Hospital

Suwon, 16499, South Korea
Allergy and Asthma Associates of Southern California - Laguna Niguel - CRN

Laguna Niguel, California, 92677, United States
Aprillus Asistencia e Investigacion de Arcis Salud SRL

CABA, Buenos Aires F.D., 1406, Argentina
Bexley Dermatology Research

Bexley, Ohio, 43209, United States
CHRU Nantes Hôtel Dieu

Nantes, 44093, France
Cahaba Dermatology & Skin Health Center, LLC

Birmingham, Alabama, 35244, United States
Center for Dermatology & Plastic Surgery - Avacare

Scottsdale, Arizona, 85260, United States
Centricity Research Columbus Dermatology

Columbus, Georgia, 31904, United States
Centrum Badan Klinicznych PI-House sp. z o.o.

Gdansk, 80-546, Poland
Centrum Nowoczesnych Terapii Dobry Lekarz Sp. z o.o.

Krakow, 31-011, Poland
China Medical University Hospital

Taichung, 404, Taiwan
Clinica Mayo de Urgencias

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Clinical Partners LLC

Johnston, Rhode Island, 02919, United States
Conexa Investigación Clínica S.A.

CABA, Buenos Aires F.D., 1012, Argentina
Cornerstone Dermatology

Coorparoo, QSL, 4151, Australia
Deluxe Health Center

Miami Lakes, Florida, 33014, United States
Dermatology Research Associates

Los Angeles, California, 90045, United States
Direct Helpers Research Center

Hialeah, Florida, 33012, United States
Dolphin Medical Research

Doral, Florida, 33172, United States
Encore Medical Research of Boynton Beach LLC

Boynton Beach, Florida, 33436, United States
Endeavor Health

Skokie, Illinois, 60026, United States
EuroMediCare Szpital Specjalistyczny z Przychodnia we Wroclawiu

Wroclaw, 54-144, Poland
Evidence Based Medical Educator Inc.

Toronto, Ontario, M5G1E2, Canada
Ginemedica Sp. z o.o.

Wroclaw, 50-414, Poland
Global Clinical Trials (Pty) Ltd - Pretoria

Pretoria, Gauteng, 0157, South Africa
Hospital A. Syggros

Athens, 16121, Greece
Hospital Clinico San Carlos - Lopez Bran

Madrid, 28040, Spain
Hospital General Universitario Dr. Balmis

Alicante, 03010, Spain
Hospital Universitario de La Plana

Villarreal de Huerva, 12540, Spain
Institute for Asthma and Allergy

Wheaton, Maryland, 20902, United States
Instituto Médico de la Fundación Estudios Clínicos

Rosario, Sante Fe, S2000DEJ, Argentina
Instituto de Especialidades de la Salud Rosario - Clínica del Tórax

Rosario, Sante Fe, 2000, Argentina
Joel Liem Medicine Professional Corporation

Windsor, Ontario, N8X 2G1, Canada
John Hopkins University

Baltimore, Maryland, 21224, United States
Kaohsiung Veterans General Hospital

Kaohsiung City, 813414, Taiwan
Kern Research

Bakersfield, California, 93301, United States
Klinika Ambroziak Dermatologia

Warsaw, 02-953, Poland
LA Universal Research Center, Inc.

Los Angeles, California, 90057, United States
Lima's Excellence In Allergy And Dermatology Research (Leader) Inc.

Hamilton, Ontario, L8L 3C3, Canada
Lynderm Research Inc

Markham, Ontario, L3P 1X3, Canada
MICS Centrum Medyczne Toruń

Torun, 87-100, Poland
Medical Center Hera EOOD

Sofia, 1510, Bulgaria
Medical Center Iskar EOOD

Sofia, 1000, Bulgaria
Medical Center Pulmovision

Sofia, 1756, Bulgaria
Medical Research of Arizona

Scottsdale, Arizona, 85251, United States
Michigan Center for Research Co., LLC

Clarkston, Michigan, 48346, United States
Midwest Clinical Research

St Louis, Missouri, 63141, United States
Montana Medical Research, Inc.

Missoula, Montana, 59808, United States
Outpatient Clinic for IP for Specialized Outpatient Medical Care in Allergology-Dr.Cholak

Razgrad, 7200, Bulgaria
Portland Allergy and Asthma

Clackamas, Oregon, 97015, United States
Rainey & Finklea San Antonio (RFSA) Dermatology

San Antonio, Texas, 78213, United States
Respiratory Medicine Research Institute of Michigan PLC

Ypsilanti, Michigan, 48197, United States
Sarasota Clinical Research

Sarasota, Florida, 34239, United States
Synapta Clinical Research Centre

Durban, KwaZulu-Natal, 4001, South Africa
The Alfred Hospital - Kern

Melbourne, Victoria, 3004, Australia
The South Bend Clinic - Avacare

South Bend, Indiana, 46617, United States
Toledo Institute for Clinical Research

Toledo, Ohio, 43617, United States
University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov EAD

Sofia, 1606, Bulgaria
University of Cape Town Lung Institute (UCTLI)

Mowbray, Western Cape, 7700, South Africa
Western Sky Medical Research

El Paso, Texas, 79912, United States
Worthwhile Clinical Trials

Benoni, Gauteng, 1501, South Africa