New hope for chronic hives: barzolvolimab shows promise in Long-Term trial
NCT ID NCT07256392
First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 4 times
Summary
This study looks at the long-term safety and effectiveness of barzolvolimab in adults with chronic spontaneous urticaria (CSU), a condition causing frequent hives and itching. Participants have already completed earlier phase 3 trials. The goal is to see how well the drug controls symptoms over time and to provide continued access to treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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About Allergy
Pretoria, Gauteng, 0181, South Africa
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Advanced Clinical Research Institute (ACRI) - Florida
Tampa, Florida, 33607, United States
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Ajou University Hospital
Suwon, 16499, South Korea
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Alina Clinical Trials LLC
Dallas, Texas, 75225, United States
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Allergy Associates of Utah
Sandy City, Utah, 84093, United States
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Allergy and Asthma Associates of Southern California - Laguna Niguel - CRN
Laguna Niguel, California, 92677, United States
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Aprillus Asistencia e Investigacion de Arcis Salud SRL
CABA, Buenos Aires F.D., 1406, Argentina
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Auni Allergy
Findlay, Ohio, 45840, United States
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Azienda Ospedaliera Ordine Mauriziano di Torino
Torino, 20128, Italy
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Bexley Dermatology Research
Bexley, Ohio, 43209, United States
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CHRU Nantes Hôtel Dieu
Nantes, 44093, France
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CHU de Nice-Hôpital L'Archet
Nice, 06202, France
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Cahaba Dermatology & Skin Health Center, LLC
Birmingham, Alabama, 35244, United States
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Center for Dermatology & Plastic Surgery - Avacare
Scottsdale, Arizona, 85260, United States
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Centricity Research Columbus Dermatology
Columbus, Georgia, 31904, United States
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Centro Internacional de Estudios Clinicos (CIEC)
Recoleta, 8420383, Chile
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Centro Respiratorio Infantil
Rosario, Sante Fe, 2000, Argentina
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Centrum Badan Klinicznych PI-House sp. z o.o.
Gdansk, 80-546, Poland
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Centrum Medyczne Pratia Poznan
Poznan, 60-185, Poland
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Centrum Nowoczesnych Terapii Dobry Lekarz Sp. z o.o.
Krakow, 31-011, Poland
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Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 833, Taiwan
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China Medical University Hospital
Taichung, 404, Taiwan
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Cityclinic Przychodnia Lekarsko Psychologiczna Matusiak Spółka Partnerska
Wroclaw, 50-566, Poland
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Clinica Mayo de Urgencias
San Miguel de Tucumán, Tucumán Province, 4000, Argentina
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Clinical Partners LLC
Johnston, Rhode Island, 02919, United States
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Cliniques Universitaires Saint-Luc
Brussels, 1200, Belgium
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Conexa Investigación Clínica S.A.
CABA, Buenos Aires F.D., 1012, Argentina
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Cornerstone Dermatology
Coorparoo, QSL, 4151, Australia
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Deluxe Health Center
Miami Lakes, Florida, 33014, United States
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Dermacross Clinica Dermatologica
Vitacura, 7630000, Chile
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Dermatology Research Associates
Los Angeles, California, 90045, United States
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Direct Helpers Research Center
Hialeah, Florida, 33012, United States
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Dolphin Medical Research
Doral, Florida, 33172, United States
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Encore Medical Research of Boynton Beach LLC
Boynton Beach, Florida, 33436, United States
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Endeavor Health
Skokie, Illinois, 60026, United States
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Enroll SpA - Dr. Manuel Barros Borgono
Providencia, 7500000, Chile
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EuroMediCare Szpital Specjalistyczny z Przychodnia we Wroclawiu
Wroclaw, 54-144, Poland
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Evidence Based Medical Educator Inc.
Toronto, Ontario, M5G1E2, Canada
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GCP, Global Clinical Professionals
St. Petersburg, Florida, 33705, United States
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Ginemedica Sp. z o.o.
Wroclaw, 50-414, Poland
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Global Clinical Trials (Pty) Ltd - Pretoria
Pretoria, Gauteng, 0157, South Africa
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Hanyang University Seoul Hospital
Seoul, 4763, South Korea
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Hospital A. Syggros
Athens, 16121, Greece
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Hospital Clinico San Carlos - Lopez Bran
Madrid, 28040, Spain
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Hospital General Universitario Dr. Balmis
Alicante, 03010, Spain
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Hospital Universitario Vall d'Hebron
Barcelona, 8035, Spain
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Hospital Universitario de La Plana
Villarreal de Huerva, 12540, Spain
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Hospital del Mar
Barcelona, 8003, Spain
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Institute for Asthma and Allergy
Wheaton, Maryland, 20902, United States
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Instituto Médico de la Fundación Estudios Clínicos
Rosario, Sante Fe, S2000DEJ, Argentina
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Instituto de Especialidades de la Salud Rosario - Clínica del Tórax
Rosario, Sante Fe, 2000, Argentina
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Joel Liem Medicine Professional Corporation
Windsor, Ontario, N8X 2G1, Canada
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John Hopkins University
Baltimore, Maryland, 21224, United States
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Kaohsiung Veterans General Hospital
Kaohsiung City, 813414, Taiwan
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Kern Research
Bakersfield, California, 93301, United States
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Klinika Ambroziak Dermatologia
Warsaw, 02-953, Poland
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LA Universal Research Center, Inc.
Los Angeles, California, 90057, United States
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Lima's Excellence In Allergy And Dermatology Research (Leader) Inc.
Hamilton, Ontario, L8L 3C3, Canada
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Lynderm Research Inc
Markham, Ontario, L3P 1X3, Canada
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MICS Centrum Medyczne Toruń
Torun, 87-100, Poland
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MacKay Memorial Hospital
Taipei, 10449, Taiwan
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Markowitz Medical PLLC dba OptiSkin Medical
New York, New York, 10128, United States
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Medical Center Hera EOOD
Sofia, 1510, Bulgaria
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Medical Center Iskar EOOD
Sofia, 1000, Bulgaria
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Medical Center Medtech Services EOOD
Haskovo, 6304, Bulgaria
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Medical Center Pulmovision
Sofia, 1756, Bulgaria
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Medical Research of Arizona
Scottsdale, Arizona, 85251, United States
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Medizinisches Versorgungszentrum DermaKiel GmbH
Kiel, Schleswig-Holstein, 24148, Germany
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Michigan Center for Research Co., LLC
Clarkston, Michigan, 48346, United States
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Midwest Clinical Research
St Louis, Missouri, 63141, United States
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Montana Medical Research, Inc.
Missoula, Montana, 59808, United States
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National Taiwan University Hospital
Taipei, 10048, Taiwan
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National Taiwan University Hospital - Hsin-Chu Branch
Hsinchu, 300, Taiwan
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Newtown Clinical Research Centre
Newtown, Gauteng, 2001, South Africa
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Outpatient Clinic for IP for Specialized Outpatient Medical Care in Allergology-Dr.Cholak
Razgrad, 7200, Bulgaria
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Portland Allergy and Asthma
Clackamas, Oregon, 97015, United States
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ProDerma
Dülmen, North Rhine-Westphalia, 48249, Germany
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Rainey & Finklea San Antonio (RFSA) Dermatology
San Antonio, Texas, 78213, United States
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Respiratory Medicine Research Institute of Michigan PLC
Ypsilanti, Michigan, 48197, United States
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Sarasota Clinical Research
Sarasota, Florida, 34239, United States
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Seoul National University Hospital
Seoul, 3080, South Korea
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Synapta Clinical Research Centre
Durban, KwaZulu-Natal, 4001, South Africa
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Synexus Polska Sp. z o.o. Oddzial w Katowicach
Katowice, 40-040, Poland
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Thammasat University Hospital
Khlong Luang, 12120, Thailand
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The Alfred Hospital - Kern
Melbourne, Victoria, 3004, Australia
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The South Bend Clinic - Avacare
South Bend, Indiana, 46617, United States
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Toledo Institute for Clinical Research
Toledo, Ohio, 43617, United States
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ULS da Região de Aveiro, EPE - Hospital Infante D. Pedro
Aveiro, 3814-501, Portugal
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ULS de Coimbra, EPE - Hospitais da Universidade de Coimbra
Coimbra, 3004-561, Portugal
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University General Hospital ''ATTIKON'' - General Hospital of West Attica H AGIA VARVARA
Chaïdári, Attica, 12462, Greece
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University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov EAD
Sofia, 1606, Bulgaria
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University of Cape Town Lung Institute (UCTLI)
Mowbray, Western Cape, 7700, South Africa
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VIDA Dermatology
Edmonton, Alberta, T6H 4J8, Canada
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Velocity Clinical Research, North London
North Finchley, N12 8BU, United Kingdom
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Western Sky Medical Research
El Paso, Texas, 79912, United States
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Worthwhile Clinical Trials
Benoni, Gauteng, 1501, South Africa
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New hope for chronic hive sufferers: phase 3 drug trial shows promise