New pill could help kids with severe eczema
NCT ID NCT03952559
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether baricitinib, an oral anti-inflammatory drug, is safe and effective for children aged 2 to 17 with moderate to severe atopic dermatitis (eczema). About 516 participants will receive either baricitinib or a placebo, along with standard topical steroids. The main goal is to see if the drug clears skin or reduces eczema severity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
baricitinib (an oral drug that targets inflammation)
What this could lead to
If it works, this could provide a new treatment option for children with moderate to severe eczema that hasn't responded to topical creams.
What could go wrong
This is a late-stage trial, but baricitinib is already approved for adults with eczema. However, results in children may differ, and side effects like infections or blood clots are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Aakash Healthcare: Super Speciality Hospital -Dwarka
Dwarka, National Capital Territory of Delhi, 110075, India
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Allergo-Derm Bakos Kft
Szolnok, Jász-Nagykun-Szolnok, 5000, Hungary
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Arké SMO S.A de C.V
Veracruz, 91900, Mexico
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B. J. Medical College & Civil Hospital
Ahmedabad, Gujarat, 380016, India
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CHOP-Centro De Especialidades De Mollabao
Pontevedra, Pontevedra [Pontevedra], 36001, Spain
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CHU de Toulouse - Hopital Larrey
Toulouse, Midi-Pyrénées, 31400, France
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Centre Hospitalier Régional Universitaire de Brest - Hôpital Morvan
Brest, Finistère, 29200, France
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Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu
Nantes, Loire-Atlantique, 44093, France
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Centre Hospitalier Universitaire de Nice - Hôpital l'Archet
Nice, Alpes-Maritimes, 6200, France
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Centro Regiomontano de Investigación
Monterrey, Nuevo León, 64060, Mexico
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Centro de Atención en Enfermedades Inflamatorias CATEI
Guadalajara, Jalisco, 44638, Mexico
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Centro de Investigaciones Metabólicas (CINME)
Ciudad Autónoma de Buenos Aires, Buenos Aires, 1027, Argentina
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Centrum Badan Klinicznych PI-House sp. z o.o.
Gdansk, Pomeranian Voivodeship, 80-546, Poland
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Chang Gung Medical Foundation-Linkou Branch
Taoyuan, 333, Taiwan
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Chang Gung Memorial Hospital - Linkou Branch
Taoyuan, 333, Taiwan
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Chang Gung Memorial Hospital at Kaohsiung
Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan
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Children's Health Research Center of RAMS
Moscow, Moscow, 115478, Russia
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Chu Saint Eloi
Montpellier, Languedoc-Roussillon, 34295, France
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Chung Shan Medical University Hospital
Taichung, 402, Taiwan
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Clinica Universidad de Navarra
Pamplona, Navarre, 31008, Spain
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Diamond Clinic
Krakow, Lesser Poland Voivodeship, 31-559, Poland
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Dokkyo Medical University Hospital
Shimotsuga, Tochigi, 321-0293, Japan
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Emek Medical Center
Afula, Northern District, 1834111, Israel
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Faculdade de Medicina do ABC
Santo André, São Paulo, 09060-870, Brazil
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Fakultni Nemocnice v Motol
Prague, Praha 5, 150 06, Czechia
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Fakultni nemocnice Bulovka
Prague, Praha 8, 180 81, Czechia
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Fakultni nemocnice Hradec Kralove
Hradec Králové, Hradec Králové, 500 05, Czechia
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Fukuyama City Hospital
Fukuyama, Hiroshima, 721-8511, Japan
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Fundacion CIDEA
Buenos Aires, Ciudad Autonoma Buenos Aires, C1121ABE, Argentina
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Fundación Respirar
Buenos Aires, C1426ABP, Argentina
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Hospital Infantil Universitario Niño Jesús
Madrid, 28009, Spain
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Hospital Sant Joan de Déu
Esplugues de Llobregat, Barcelona [Barcelona], 8950, Spain
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Hospital Universitario Dr. Jose Eleuterio Gonzalez
Monterrey, Nuevo León, 66460, Mexico
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hospital Universitario Puerta de Hierro Majadahonda
Majadahonda, Madrid, Comunidad de, 28222, Spain
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Hospital Universitario Quironsalud Madrid
Pozuelo de Alarcón, Madrid, 28223, Spain
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Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
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Hospital do Servidor Público Estadual - IAMSPE - centro de estudos urológicos
São Paulo, 04039-901, Brazil
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Hôpital Saint Vincent de Paul
Lille, Hauts-de-France, 59020, France
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Hôpitaux Drôme Nord - Romans
Romans-sur-Isère, Drôme, 26102, France
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IBPClin - Instituto Brasil de Pesquisa Clínica
Rio de Janeiro, 22241-180, Brazil
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IDERJ - Instituto de Dermatologia e Estética do Brasil
Rio de Janeiro, 22470-220, Brazil
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Instituto de Investigaciones Aplicadas a la Neurociencia A.C.
Durango, 34000, Mexico
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Instituto de Neumonología Y Dermatología
Capital Federal, Buenos Aires, 1425, Argentina
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Katholisches Kinderkrankenhaus Wilhelmstift
Hamburg, 22149, Germany
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Krasnodar Clinical Skin and Venereal Diseases Dispensary
Krasnodar, Krasnodarskiy Kray, 354057, Russia
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Kume Clinic
Sakai, Osaka, 593-8324, Japan
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Matsuda Tomoko Dermatological Clinic
Fukuoka, 819-0167, Japan
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Medizinische Universität Graz
Graz, Styria, 8036, Austria
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Medizinische Universität Wien
Vienna, State of Vienna, 1090, Austria
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Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology - Central branch
Moscow, Moscow, 127473, Russia
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Nagoya Medical Center
Nagoya, Aichi-ken, 460-0001, Japan
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National Hospital Organization Sagamihara National Hospital
Sagamihara, Kanagawa, 252-0392, Japan
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National Mie Hospital
Tsu, Mie-ken, 514-0125, Japan
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National Taiwan University Hospital
Taipei, 10002, Taiwan
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Nemocnice AGEL Novy Jicin a.s.
Nový Jičín, Nový Jičín, 741 01, Czechia
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Queen's Medical Centre, Nottingham University Hospitals
Nottingham, Nottinghamshire, NG7 2UH, United Kingdom
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Royal Children's Hospital
Melbourne, Victoria, 3052, Australia
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Royal Hospital for Sick Children
Glasgow, Glasgow City, G514TF, United Kingdom
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Sanatorium profesora Arenbergera
Prague, 128 00, Czechia
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Senri-Chuo Hanafusa Dermatology Clinic
Toyonaka, Osaka, 560-0085, Japan
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Sheba Medical Center
Ramat Gan, Central District, 5262100, Israel
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Shinjuku Minamiguchi Hifuka
Tokyo, 160-0023, Japan
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Sir Ganga Ram Hospital
New Delhi, National Capital Territory of Delhi, 110060, India
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Soroka Medical Center
Beersheba, Southern District, 8410101, Israel
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Sourasky Medical Center
Tel Aviv, Tell Abīb, 6423906, Israel
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Sozialmedizinisches Zentrum Ost/Donauspital
Vienna, State of Vienna, 1220, Austria
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Specjalistyczne Gabinety Lekarskie "DERMED" Anna Kaszuba
Lodz, Łódź Voivodeship, 90-265, Poland
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St Thomas's Hospital
London, London, City of, SE1 7EH, United Kingdom
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Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ
Szeged, Csongrád megye, 6720, Hungary
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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Takeda Dermatology Skincare Clinic
Sapporo, Hokkaido, 004-0063, Japan
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The Children's Hospital at Westmead
Westmead, New South Wales, 2145, Australia
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Tula Regional Clinical Dermatovenerological Dispensary
Tula, Tula Oblast, 300053, Russia
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Universitaetsklinikum Carl Gustav Carus Dresden
Dresden, Saxony, 01307, Germany
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Universitätsklinikum Frankfurt
Frankfurt am Main, Hesse, 60590, Germany
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Universitätsklinikum Münster
Münster, North Rhine-Westphalia, 48149, Germany
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Veracity Clinical Research
Woolloongabba, Queensland, 4102, Australia