New NASH drug candidate BAR502 enters first human safety trial

NCT ID NCT06705998

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This is the first time BAR502, an experimental drug for NASH (a serious liver condition), is being tested in humans. The study involves 52 healthy adults to check the drug's safety, tolerability, and how the body processes it. Participants receive either a single dose or multiple doses of BAR502 or a placebo. This early-stage trial does not aim to treat NASH but to gather essential safety data for future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BAR502 (oral tablet)

What this could lead to

If successful, this early study could pave the way for future trials of BAR502 as a potential treatment for NASH (a liver disease).

What could go wrong

This is a very early Phase 1 trial in only 52 healthy people, not patients. It primarily checks safety, not whether the drug works for NASH. Many drugs fail at this stage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CROSS Research S.A. Phase I Unit

    RECRUITING

    Arzo, CH-6864, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••