Could a bacterial extract help tame stubborn hives?
NCT ID NCT07557888
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding a bacterial lysate (OM-85) to standard antihistamines can better control chronic spontaneous urticaria (CSU), also known as chronic hives. Researchers will observe 132 adults who have not responded well to antihistamines alone. The main goal is to see if the combination reduces hives activity over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bacterial lysate (OM-85) combined with antihistamines
- What this could lead to
- If it works, this could offer a new way to control chronic hives for people who don't get enough relief from antihistamines alone.
- What could go wrong
- This is an early observational study, not a randomized trial, so results may be less reliable. It's also small (132 people) and only at one center, so findings may not apply broadly.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Fourth Affiliated Hospital Zhejiang University School of Medicine
Yiwu, Zhejiang, 322000, China
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Other studies related to the condition(s) this trial covers.
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